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Primary defects in the lens underlie complex anterior segment abnormalities of the Pax6 heterozygous eye
We describe lens defects in heterozygous small eye mice, and autonomous deficiencies of Pax6(+/−) cells in the developing lens of Pax6(+/+) ↔ Pax6(+/−) chimeras. Two separate defects of the lens were identified by analyzing the distribution of heterozygous cells in chimeras: Pax6(+/−) cells are less...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC55513/ https://ncbi.nlm.nih.gov/pubmed/11481423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161144098 |
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