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Effects of Elevated Pax6 Expression and Genetic Background on Mouse Eye Development

PURPOSE: To analyze the effects of Pax6 overexpression and its interaction with genetic background on eye development. METHODS: Histologic features of eyes from hemizygous PAX77(+/−) transgenic (high Pax6 gene dose) and wild-type mice were compared on different genetic backgrounds. Experimental PAX7...

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Detalhes bibliográficos
Main Authors: Chanas, Simon A., Collinson, J. Martin, Ramaesh, Thaya, Dorà, Natalie, Kleinjan, Dirk A., Hill, Robert E., West, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763115/
https://ncbi.nlm.nih.gov/pubmed/19387074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1630
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