Prodepressant- and anxiogenic-like effects of serotonin-selective, but not noradrenaline-selective, antidepressant agents in mice lacking α2-containing GABA(A) receptors

Deficits in neuronal inhibition via gamma-aminobutyric acid (GABA) type A receptors (GABAA-Rs) are implicated in the pathophysiology of major depressive disorder and the therapeutic effects of current antidepressant treatments, however, the relevant GABAA-R subtype as defined by its alpha subunit is...

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Bibliographic Details
Published in:Behav Brain Res
Main Authors: Benham, Rebecca S., Hewage, Nishani B., Suckow, Raymond F., Engin, Elif, Rudolph, Uwe
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551052/
https://ncbi.nlm.nih.gov/pubmed/28587819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2017.05.063
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