Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism

BACKGROUND: Statins are a class of therapeutics used to regulate serum cholesterol and reduce the risk of heart disease. Although statins are highly effective in removing cholesterol from the blood, their consumption has been linked to potential adverse effects in some individuals. The most common e...

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Detalhes bibliográficos
Publicado no:Microbiome
Main Authors: Caparrós-Martín, Jose A., Lareu, Ricky R., Ramsay, Joshua P., Peplies, Jörg, Jerry Reen, F., Headlam, Henrietta A., Ward, Natalie C., Croft, Kevin D., Newsholme, Philip, Hughes, Jeffery D., O’Gara, Fergal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550934/
https://ncbi.nlm.nih.gov/pubmed/28793934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-017-0312-4
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