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p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD
Cytokines often deliver simultaneous, yet distinct, cell growth and cell survival signals. The 70-kDa ribosomal protein S6 kinase (p70S6K) is known to regulate cell growth by inducing protein synthesis components. We purified membrane-based p70S6K as a kinase responsible for site-specific phosphoryl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC55509/ https://ncbi.nlm.nih.gov/pubmed/11493700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171301998 |
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