Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells

Sorcin is a calcium binding protein that plays an important role in multidrug resistance (MDR) in tumors, since its expression confers resistance to doxorubicin and to other chemotherapeutic drugs. In this study, we show that Sorcin is able to bind doxorubicin, vincristine, paclitaxel and cisplatin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Genovese, Ilaria, Fiorillo, Annarita, Ilari, Andrea, Masciarelli, Silvia, Fazi, Francesco, Colotti, Gianni
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550883/
https://ncbi.nlm.nih.gov/pubmed/28726784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.342
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