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Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells
Sorcin is a calcium binding protein that plays an important role in multidrug resistance (MDR) in tumors, since its expression confers resistance to doxorubicin and to other chemotherapeutic drugs. In this study, we show that Sorcin is able to bind doxorubicin, vincristine, paclitaxel and cisplatin...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5550883/ https://ncbi.nlm.nih.gov/pubmed/28726784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.342 |
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