Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation

Diabetic nephropathy (DN) is one of the most lethal complications of diabetes mellitus with metabolic disorders and chronic inflammation. Although the cytokine IL-22 was initially implicated in the pathogenesis of chronic inflammatory diseases, recent studies suggested that IL-22 could suppress infl...

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Udgivet i:Cell Death Dis
Main Authors: Wang, Shaofei, Li, Yubin, Fan, Jiajun, Zhang, Xuyao, Luan, Jingyun, Bian, Qi, Ding, Tao, Wang, Yichen, Wang, Ziyu, Song, Ping, Cui, Daxiang, Mei, Xiaobin, Ju, Dianwen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550847/
https://ncbi.nlm.nih.gov/pubmed/28726774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.292
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