Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury

Rationale: Interleukin 22 (IL-22) is an epithelial survival cytokine that is at present being explored as therapeutic agents for acute and chronic liver injury. However, its molecular basis of protective activities remains poorly understood. Methods: Here we demonstrate that IL-22 inhibits the deter...

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Bibliographic Details
Published in:Theranostics
Main Authors: Chen, Wei, Zai, Wenjing, Fan, Jiajun, Zhang, Xuyao, Zeng, Xian, Luan, Jingyun, Wang, Yichen, Shen, Yilan, Wang, Ziyu, Dai, Shixuan, Fang, Si, Zhao, Zhen, Ju, Dianwen
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254999/
https://ncbi.nlm.nih.gov/pubmed/32483425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43894
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