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Dickkopf1 destabilizes atherosclerotic plaques and promotes plaque formation by inducing apoptosis of endothelial cells through activation of ER stress

Several clinical studies reported that Dickkopf1 (DKK1) plasma levels are correlated with atherosclerosis. However, the impact of DKK1 on the formation and vulnerability of atherosclerotic plaques remains elusive. This study investigated DKK1’s effects on enlargement and destabilization of plaques b...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Di, Mingxue, Wang, Lin, Li, Mengmeng, Zhang, Yu, Liu, Xinxin, Zeng, Renya, Wang, Han, Chen, Yifei, Chen, Weijia, Zhang, Yun, Zhang, Mei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550842/
https://ncbi.nlm.nih.gov/pubmed/28703797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.277
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