Dickkopf1 destabilizes atherosclerotic plaques and promotes plaque formation by inducing apoptosis of endothelial cells through activation of ER stress

Several clinical studies reported that Dickkopf1 (DKK1) plasma levels are correlated with atherosclerosis. However, the impact of DKK1 on the formation and vulnerability of atherosclerotic plaques remains elusive. This study investigated DKK1’s effects on enlargement and destabilization of plaques b...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Di, Mingxue, Wang, Lin, Li, Mengmeng, Zhang, Yu, Liu, Xinxin, Zeng, Renya, Wang, Han, Chen, Yifei, Chen, Weijia, Zhang, Yun, Zhang, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550842/
https://ncbi.nlm.nih.gov/pubmed/28703797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.277
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