Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy

Hepatocellular carcinoma (HCC) is one of the most lethal and prevalent cancers worldwide. CD147 (EMMPRIN or basigin) is a leading gene relating to hepatocarcinogenesis and metastasis, and is detected in transmembrane, exosome or circulating forms in HCC patients. The endosome recycling of CD147 furt...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Wu, Bo, Cui, Jian, Yang, Xiang-Min, Liu, Zhen-Yu, Song, Fei, Li, Ling, Jiang, Jian-Li, Chen, Zhi-Nan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550841/
https://ncbi.nlm.nih.gov/pubmed/28703811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.251
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