Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy

Hepatocellular carcinoma (HCC) is one of the most lethal and prevalent cancers worldwide. CD147 (EMMPRIN or basigin) is a leading gene relating to hepatocarcinogenesis and metastasis, and is detected in transmembrane, exosome or circulating forms in HCC patients. The endosome recycling of CD147 furt...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wu, Bo, Cui, Jian, Yang, Xiang-Min, Liu, Zhen-Yu, Song, Fei, Li, Ling, Jiang, Jian-Li, Chen, Zhi-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550841/
https://ncbi.nlm.nih.gov/pubmed/28703811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.251
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