Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy

Hepatocellular carcinoma (HCC) is one of the most lethal and prevalent cancers worldwide. CD147 (EMMPRIN or basigin) is a leading gene relating to hepatocarcinogenesis and metastasis, and is detected in transmembrane, exosome or circulating forms in HCC patients. The endosome recycling of CD147 furt...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Wu, Bo, Cui, Jian, Yang, Xiang-Min, Liu, Zhen-Yu, Song, Fei, Li, Ling, Jiang, Jian-Li, Chen, Zhi-Nan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550841/
https://ncbi.nlm.nih.gov/pubmed/28703811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.251
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