Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence

Clostridium difficile is a spore-forming anaerobic bacterium that causes colitis in patients with disrupted colonic microbiota. While some individuals are asymptomatic C. difficile carriers, symptomatic disease ranges from mild diarrhea to potentially lethal toxic megacolon. The wide disease spectru...

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Gepubliceerd in:mBio
Hoofdauteurs: Lewis, Brittany B., Carter, Rebecca A., Ling, Lilan, Leiner, Ingrid, Taur, Ying, Kamboj, Mini, Dubberke, Erik R., Xavier, Joao, Pamer, Eric G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550754/
https://ncbi.nlm.nih.gov/pubmed/28790208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00885-17
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