Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence

Clostridium difficile is a spore-forming anaerobic bacterium that causes colitis in patients with disrupted colonic microbiota. While some individuals are asymptomatic C. difficile carriers, symptomatic disease ranges from mild diarrhea to potentially lethal toxic megacolon. The wide disease spectru...

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Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Lewis, Brittany B., Carter, Rebecca A., Ling, Lilan, Leiner, Ingrid, Taur, Ying, Kamboj, Mini, Dubberke, Erik R., Xavier, Joao, Pamer, Eric G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550754/
https://ncbi.nlm.nih.gov/pubmed/28790208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00885-17
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