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Pinacidil reduces neuronal apoptosis following cerebral ischemia-reperfusion in rats through both mitochondrial and death-receptor signal pathways

OBJECTIVE: To investigate effect of pinacidil, an ATP sensitive potassium channel (K(ATP)) opener, on the neuronal apoptosis and its signaling transduction mechanism following focal cerebral ischemia-reperfusion in rats. METHODS: One hundred male Wistar rats were randomly divided into four groups: A...

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Podrobná bibliografie
Vydáno v:Neurosci Bull
Hlavní autoři: Zhang, Hong, Song, Li-Chun, Liu, Yan-Yan, Ma, Ying, Lu, Yong-Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550628/
https://ncbi.nlm.nih.gov/pubmed/17612592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-007-0021-2
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