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Pinacidil reduces neuronal apoptosis following cerebral ischemia-reperfusion in rats through both mitochondrial and death-receptor signal pathways
OBJECTIVE: To investigate effect of pinacidil, an ATP sensitive potassium channel (K(ATP)) opener, on the neuronal apoptosis and its signaling transduction mechanism following focal cerebral ischemia-reperfusion in rats. METHODS: One hundred male Wistar rats were randomly divided into four groups: A...
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| Publicado en: | Neurosci Bull |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5550628/ https://ncbi.nlm.nih.gov/pubmed/17612592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-007-0021-2 |
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