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Ebola virus VP24 interacts with NP to facilitate nucleocapsid assembly and genome packaging

Ebola virus causes devastating hemorrhagic fever outbreaks for which no approved therapeutic exists. The viral nucleocapsid, which is minimally composed of the proteins NP, VP35, and VP24, represents an attractive target for drug development; however, the molecular determinants that govern the inter...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Banadyga, Logan, Hoenen, Thomas, Ambroggio, Xavier, Dunham, Eric, Groseth, Allison, Ebihara, Hideki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550494/
https://ncbi.nlm.nih.gov/pubmed/28794491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08167-8
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