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Ebola virus VP24 interacts with NP to facilitate nucleocapsid assembly and genome packaging

Ebola virus causes devastating hemorrhagic fever outbreaks for which no approved therapeutic exists. The viral nucleocapsid, which is minimally composed of the proteins NP, VP35, and VP24, represents an attractive target for drug development; however, the molecular determinants that govern the inter...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Banadyga, Logan, Hoenen, Thomas, Ambroggio, Xavier, Dunham, Eric, Groseth, Allison, Ebihara, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550494/
https://ncbi.nlm.nih.gov/pubmed/28794491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08167-8
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