The Conserved Lysine-265 Allosterically Modulates Nucleotide- and Actin-binding Site Coupling in Myosin-2

Myosin motor proteins convert chemical energy into force and movement through their interactions with nucleotide and filamentous actin (F-actin). The evolutionarily conserved lysine-265 (K265) of the myosin-2 motor from Dictyostelium discoideum (Dd) is proposed to be a key residue in an allosteric c...

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Publicado no:Sci Rep
Main Authors: Behrens, Vincent A., Münnich, Stefan, Adler-Gunzelmann, Georg, Thiel, Claudia, Henn, Arnon, Latham, Sharissa L., Taft, Manuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550493/
https://ncbi.nlm.nih.gov/pubmed/28794442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07933-y
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