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The Myosin C-Loop Is an Allosteric Actin Contact Sensor in Actomyosin

Actin and myosin form the molecular motor in muscle. Myosin is the enzyme performing ATP hydrolysis under the allosteric control of actin such that actin binding initiates product release and force generation in the myosin power stroke. Non-equilibrium Monte Carlo molecular dynamics simulation of th...

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Detalhes bibliográficos
Main Authors: Ajtai, Katalin, Halstead, Miriam F., Nyitrai, Miklós, Penheiter, Alan R., Zheng, Ye, Burghardt, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759872/
https://ncbi.nlm.nih.gov/pubmed/19408946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900584q
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