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Cardiac and skeletal actin substrates uniquely tune cardiac myosin strain-dependent mechanics

Cardiac ventricular myosin (βmys) translates actin by transducing ATP free energy into mechanical work during muscle contraction. Unitary βmys translation of actin is the step-size. In vitro and in vivo βmys regulates contractile force and velocity autonomously by remixing three different step-sizes...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Wang, Yihua, Ajtai, Katalin, Burghardt, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282072/
https://ncbi.nlm.nih.gov/pubmed/30463911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.180143
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