The miR-183 family cluster alters zinc homeostasis in benign prostate cells, organoids and prostate cancer xenografts

The miR-183 cluster, which is comprised of paralogous miRs-183, -96 and -182, is overexpressed in many cancers, including prostate adenocarcinoma (PCa). Prior studies showed that overexpression of individual pre-miRs-182, -96 and -183 in prostate cells decreased zinc import, which is a characteristi...

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Publicat a:Sci Rep
Autors principals: Dambal, Shweta, Baumann, Bethany, McCray, Tara, Williams, LaTanya, Richards, Zachary, Deaton, Ryan, Prins, Gail S., Nonn, Larisa
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550464/
https://ncbi.nlm.nih.gov/pubmed/28794468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07979-y
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