Selectively Inducing Cancer Cell Death by Intracellular Enzyme-Instructed Self-Assembly (EISA) of Dipeptide Derivatives

Tight ligand-receptor binding, paradoxically, is a major root of drug resistance in cancer chemotherapy. To address this problem, instead of using conventional inhibitors or ligands, we focus on the development of a novel process—enzyme-instructed self-assembly (EISA)—to kill cancer cells selectivel...

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發表在:Adv Healthc Mater
Main Authors: Li, Jie, Shi, Junfeng, Medina, Jamie E., Zhou, Jie, Du, Xuewen, Wang, Huaimin, Yang, Cuihong, Liu, Jianfeng, Yang, Zhimou, Dinulescu, Daniela M., Xu, Bing
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550337/
https://ncbi.nlm.nih.gov/pubmed/28233466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201601400
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