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Constraint and Contingency Pervade the Emergence of Novel Phenotypes in Complex Metabolic Systems

An evolutionary constraint is a bias or limitation in phenotypic variation that a biological system produces. We know examples of such constraints, but we have no systematic understanding about their extent and causes for any one biological system. We here study metabolisms, genomically encoded comp...

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Vydáno v:Biophys J
Hlavní autoři: Hosseini, Sayed-Rzgar, Wagner, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550299/
https://ncbi.nlm.nih.gov/pubmed/28793223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.034
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