Schistosome egg antigens, including the glycoprotein IPSE/alpha-1, trigger the development of regulatory B cells

Infection with the helminth Schistosoma (S.) mansoni drives the development of interleukin (IL)-10-producing regulatory B (Breg) cells in mice and man, which have the capacity to reduce experimental allergic airway inflammation and are thus of high therapeutic interest. However, both the involved an...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Haeberlein, Simone, Obieglo, Katja, Ozir-Fazalalikhan, Arifa, Chayé, Mathilde A. M., Veninga, Henrike, van der Vlugt, Luciën E. P. M., Voskamp, Astrid, Boon, Louis, den Haan, Joke M. M., Westerhof, Lotte B., Wilbers, Ruud H. P., Schots, Arjen, Schramm, Gabriele, Hokke, Cornelis H., Smits, Hermelijn H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550006/
https://ncbi.nlm.nih.gov/pubmed/28753651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006539
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