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S(N)Ar Catalysis Enhanced by an Aromatic Donor-Acceptor Interaction; Facile Access to Chlorinated Polyfluoroarenes

Selective catalytic S(N)Ar reaction of polyfluoroaryl C–F bonds with chloride is shown. Stoichiometric TMSCl makes the reaction exergonic and allows catalysis, which involves ground state elevation of chloride, aromatic donor-acceptor interactions, and stabilization of the Meisenheimer complex. Trad...

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Publicado en:Chem Commun (Camb)
Main Authors: Senaweera, Sameera, Weaver, Jimmie D.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549941/
https://ncbi.nlm.nih.gov/pubmed/28634609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc03996d
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