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S(N)Ar Catalysis Enhanced by an Aromatic Donor-Acceptor Interaction; Facile Access to Chlorinated Polyfluoroarenes

Selective catalytic S(N)Ar reaction of polyfluoroaryl C–F bonds with chloride is shown. Stoichiometric TMSCl makes the reaction exergonic and allows catalysis, which involves ground state elevation of chloride, aromatic donor-acceptor interactions, and stabilization of the Meisenheimer complex. Trad...

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Publicat a:Chem Commun (Camb)
Autors principals: Senaweera, Sameera, Weaver, Jimmie D.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549941/
https://ncbi.nlm.nih.gov/pubmed/28634609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc03996d
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