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Screening of nucleotide variations in genomic sequences encoding charged protein regions in the human genome

BACKGROUND: Studying genetic variation distribution in proteins containing charged regions, called charge clusters (CCs), is of great interest to unravel their functional role. Charge clusters are 20 to 75 residue segments with high net positive charge, high net negative charge, or high total charge...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Belmabrouk, Sabrine, Kharrat, Najla, Abdelhedi, Rania, Ben Ayed, Amine, Benmarzoug, Riadh, Rebai, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549384/
https://ncbi.nlm.nih.gov/pubmed/28789634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4000-3
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