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Role of AmpR in the High Expression of the Plasmid-Encoded AmpC β-Lactamase CFE-1

CFE-1 is a unique plasmid-encoded AmpC β-lactamase with the regulator gene ampR. It imparts high resistance to most cephalosporins with constitutive high-level β-lactamase activity. Here, the β-lactamase activities and expression levels of ampC with or without ampR were investigated. Results suggest...

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Bibliografiske detaljer
Udgivet i:mSphere
Main Authors: Nakano, Ryuichi, Nakano, Akiyo, Yano, Hisakazu, Okamoto, Ryoichi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549177/
https://ncbi.nlm.nih.gov/pubmed/28808689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00192-17
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