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Gene Mutations Responsible for Overexpression of AmpC β-Lactamase in Some Clinical Isolates of Enterobacter cloacae

AmpC regulatory genes in 21 ceftazidime-resistant clinical isolates of Enterobacter cloacae (MICs of ≥16 μg/ml) were characterized. All isolates exhibited AmpC overproduction due to AmpD mutation. Additionally, we found two AmpR mutants among the isolates. This is the first report of chromosomal amp...

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Detalhes bibliográficos
Main Authors: Kaneko, Kenichi, Okamoto, Ryoichi, Nakano, Ryuichi, Kawakami, Sayoko, Inoue, Matsuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151923/
https://ncbi.nlm.nih.gov/pubmed/15956430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.6.2955-2958.2005
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