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Envelope-specific antibodies and antibody-derived molecules for treating and curing HIV infection
HIV-1 is a retrovirus that integrates into host chromatin and can remain transcriptionally quiescent in a pool of immune cells. This characteristic enables HIV-1 to evade both host immune responses and antiretroviral drugs, leading to persistent infection. Upon reactivation of proviral gene expressi...
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| Publicado no: | Nat Rev Drug Discov |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5549020/ https://ncbi.nlm.nih.gov/pubmed/27725635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.173 |
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