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Envelope-specific antibodies and antibody-derived molecules for treating and curing HIV infection

HIV-1 is a retrovirus that integrates into host chromatin and can remain transcriptionally quiescent in a pool of immune cells. This characteristic enables HIV-1 to evade both host immune responses and antiretroviral drugs, leading to persistent infection. Upon reactivation of proviral gene expressi...

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Bibliografiska uppgifter
I publikationen:Nat Rev Drug Discov
Huvudupphovsmän: Ferrari, Guido, Haynes, Barton F., Koenig, Scott, Nordstrom, Jeffrey L., Margolis, David M., Tomaras, Georgia D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549020/
https://ncbi.nlm.nih.gov/pubmed/27725635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.173
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