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Safety, immunogenicity, and cross-species protection of a plasmid DNA encoding Plasmodium falciparum SERA5 polypeptide, microbial epitopes and chemokine genes in mice and olive baboons

Incorporation of biomolecular epitopes to malarial antigens should be explored in the development of strain-transcending malarial vaccines. The present study sought to determine safety, immunogenicity and cross-species efficacy ofPlasmodium falciparum serine repeat antigen 5 polypeptide co-expressed...

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Bibliographic Details
Published in:J Biomed Res
Main Authors: Onkoba, Nyamongo, Mumo, Ruth M., Ochanda, Horace, Omwandho, Charles, Ozwara, Hastings S., Egwang, Thomas G.
Format: Artigo
Language:Inglês
Published: Editorial Department of Journal of Biomedical Research 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548993/
https://ncbi.nlm.nih.gov/pubmed/28808204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.31.20160025
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