Safety, immunogenicity, and cross-species protection of a plasmid DNA encoding Plasmodium falciparum SERA5 polypeptide, microbial epitopes and chemokine genes in mice and olive baboons

Incorporation of biomolecular epitopes to malarial antigens should be explored in the development of strain-transcending malarial vaccines. The present study sought to determine safety, immunogenicity and cross-species efficacy ofPlasmodium falciparum serine repeat antigen 5 polypeptide co-expressed...

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Detalhes bibliográficos
Publicado no:J Biomed Res
Main Authors: Onkoba, Nyamongo, Mumo, Ruth M., Ochanda, Horace, Omwandho, Charles, Ozwara, Hastings S., Egwang, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548993/
https://ncbi.nlm.nih.gov/pubmed/28808204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.31.20160025
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