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Selective cytotoxicity of a novel immunotoxin based on pulchellin A chain for cells expressing HIV envelope

Immunotoxins (ITs), which consist of antibodies conjugated to toxins, have been proposed as a treatment for cancer and chronic infections. To develop and improve the ITs, different toxins such as ricin, have been used, aiming for higher efficacy against target cells. The toxin pulchellin, isolated f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sadraeian, Mohammad, Guimarães, Francisco E. G., Araújo, Ana P. U., Worthylake, David K., LeCour, Louis Jr., Pincus, Seth H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548917/
https://ncbi.nlm.nih.gov/pubmed/28790381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08037-3
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