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Single-cell analyses identify bioengineered niches for enhanced maintenance of hematopoietic stem cells
The in vitro expansion of long-term hematopoietic stem cells (HSCs) remains a substantial challenge, largely because of our limited understanding of the mechanisms that control HSC fate choices. Using single-cell multigene expression analysis and time-lapse microscopy, here we define gene expression...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5548907/ https://ncbi.nlm.nih.gov/pubmed/28790449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00291-3 |
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