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A Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence

Infection of mice with strains of Plasmodium yoelii parasites can result in different pathology, but molecular mechanisms to explain this variation are unclear. Here we show that a P. yoelii gene encoding a HECT-like E3 ubiquitin ligase (Pyheul) influences parasitemia and host mortality. We genetica...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Nair, Sethu C., Xu, Ruixue, Pattaradilokrat, Sittiporn, Wu, Jian, Qi, Yanwei, Zilversmit, Martine, Ganesan, Sundar, Nagarajan, Vijayaraj, Eastman, Richard T., Orandle, Marlene S., Tan, John C., Myers, Timothy G., Liu, Shengfa, Long, Carole A., Li, Jian, Su, Xin-zhuan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548792/
https://ncbi.nlm.nih.gov/pubmed/28790316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00267-3
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