A Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence

Infection of mice with strains of Plasmodium yoelii parasites can result in different pathology, but molecular mechanisms to explain this variation are unclear. Here we show that a P. yoelii gene encoding a HECT-like E3 ubiquitin ligase (Pyheul) influences parasitemia and host mortality. We genetica...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Nair, Sethu C., Xu, Ruixue, Pattaradilokrat, Sittiporn, Wu, Jian, Qi, Yanwei, Zilversmit, Martine, Ganesan, Sundar, Nagarajan, Vijayaraj, Eastman, Richard T., Orandle, Marlene S., Tan, John C., Myers, Timothy G., Liu, Shengfa, Long, Carole A., Li, Jian, Su, Xin-zhuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548792/
https://ncbi.nlm.nih.gov/pubmed/28790316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00267-3
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