The H7N9 influenza A virus infection results in lethal inflammation in the mammalian host via the NLRP3-caspase-1 inflammasome

The avian origin influenza A virus (IAV) H7N9 has caused a considerable number of human infections associated with high rates of death since its emergence in 2013. As a vital component of the host innate immune system, the nucleotide-binding domain leucine-rich repeat containing receptor, pyrin doma...

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Vydáno v:Sci Rep
Hlavní autoři: Ren, Rongrong, Wu, Shuxian, Cai, Jialin, Yang, Yuqin, Ren, Xiaonan, Feng, Yanling, Chen, Lixiang, Qin, Boyin, Xu, Chunhua, Yang, Hua, Song, Zhigang, Tian, Di, Hu, Yunwen, Zhou, Xiaohui, Meng, Guangxun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548739/
https://ncbi.nlm.nih.gov/pubmed/28790324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07384-5
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