Dietary α-cyclodextrin reduces atherosclerosis and modifies gut flora in apolipoprotein E-deficient mice

SCOPE: α-Cyclodextrin (α-CD), a cyclic polymer of glucose, has been shown to lower plasma cholesterol in animals and humans; however, its effect on atherosclerosis has not been previously described. METHODS AND RESULTS: apoE-knockout mice were fed either low-fat diet (LFD; 5.2% fat, w/w), or Western...

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Detalhes bibliográficos
Publicado no:Mol Nutr Food Res
Main Authors: Sakurai, Toshihiro, Sakurai, Akiko, Chen, Ye, Vaisman, Boris L., Amar, Marcelo J., Pryor, Milton, Thacker, Seth G., Zhang, Xue, Wang, Xujing, Zhang, Yubo, Zhu, Jun, Yang, Zhi-Hong, Freeman, Lita A., Remaley, Alan T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548635/
https://ncbi.nlm.nih.gov/pubmed/28102587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201600804
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