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Antigen acquisition enables newly arriving B cells to enter ongoing immunization-induced germinal centers

Modern vaccines must be aimed to generate long-lasting, high-affinity and broadly neutralizing antibody responses against pathogens. The diversity of B cell clones recruited into Germinal Center (GC) responses is likely to be important for the antigen neutralization potential of the antibody-secreti...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Turner, Jackson S., Benet, Zachary L., Grigorova, Irina L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548600/
https://ncbi.nlm.nih.gov/pubmed/28687657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700267
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