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Transiently antigen-primed B cells return to naive-like state in absence of T-cell help

The perspective that naive B-cell recognition of antigen in the absence of T-cell help causes cell death or anergy is supported by in vivo studies of B cells that are continuously exposed to self-antigens. However, intravital imaging suggests that early B-cell recognition of large foreign antigens m...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Turner, Jackson S., Marthi, Matangi, Benet, Zachary L., Grigorova, Irina
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413946/
https://ncbi.nlm.nih.gov/pubmed/28429719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15072
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