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Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers
The majority of human breast cancer is estrogen receptor alpha (ER) positive. While anti-estrogens/aromatase inhibitors are initially effective, resistance to these drugs commonly develops. Therapy-resistant tumors often retain ER signaling, via interaction with critical oncogenic coregulator protei...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5548489/ https://ncbi.nlm.nih.gov/pubmed/28786813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26857 |
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