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Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector

Crigler–Najjar syndrome is a recessively inherited disorder characterized by severe unconjugated hyperbilirubinemia caused by a deficiency of uridine diphospho-glucuronosyl transferase 1A1. Current therapy relies on phototherapy to prevent kernicterus, but liver transplantation presently is the only...

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Detalhes bibliográficos
Main Authors: Toietta, Gabriele, Mane, Viraj P., Norona, Wilma S., Finegold, Milton J., Ng, Philip, McDonagh, Antony F., Beaudet, Arthur L., Lee, Brendan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC554836/
https://ncbi.nlm.nih.gov/pubmed/15753292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500930102
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