A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist

IL-22 is an IL-10 homologue that binds to and signals through the class II cytokine receptor heterodimer IL-22RA1/CRF2–4. IL-22 is produced by T cells and induces the production of acute-phase reactants in vitro and in vivo, suggesting its involvement in inflammation. Here we report the identificati...

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Bibliografski detalji
Glavni autori: Xu, Wenfeng, Presnell, Scott R., Parrish-Novak, Julia, Kindsvogel, Wayne, Jaspers, Steve, Chen, Zhi, Dillon, Stacey R., Gao, Zeren, Gilbert, Teresa, Madden, Karen, Schlutsmeyer, Stacy, Yao, Lena, Whitmore, Theodore E., Chandrasekher, Yasmin, Grant, Francis J., Maurer, Mark, Jelinek, Laura, Storey, Harold, Brender, Ty, Hammond, Angie, Topouzis, Stavros, Clegg, Christopher H., Foster, Donald C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2001
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC55483/
https://ncbi.nlm.nih.gov/pubmed/11481447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171303198
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