A Role for Primary Cilia in Aortic Valve Development and Disease

BACKGROUND: Bicuspid aortic valve (BAV) disease is the most common congenital heart defect affecting 0.5–1.2% of the population and causes significant morbidity and mortality. Only a few genes have been identified in pedigrees and no single gene-model explains BAV inheritance, thus supporting a comp...

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Bibliografiske detaljer
Udgivet i:Dev Dyn
Main Authors: Toomer, Katelynn A, Fulmer, Diana, Guo, Lilong, Drohan, Alex, Peterson, Neal, Swanson, Paige, Brooks, Brittany, Mukherjee, Rupak, Body, Simon, Lipschutz, Josh, Wessels, Andy, Norris, Russell A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548133/
https://ncbi.nlm.nih.gov/pubmed/28556366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24524
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