IL-4/IL-13–mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury

Cytokines IL-4 and IL-13 play important roles in polarization of macrophages/dendritic cells to an M2 phenotype, which is important for recovery from acute kidney injury. Both IL-4 and IL-13 activate JAK3/STAT6 signaling. In mice with diphtheria toxin receptor expression in proximal tubules (selecti...

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Gepubliceerd in:Kidney Int
Hoofdauteurs: Zhang, Ming-Zhi, Wang, Xin, Wang, Yinqiu, Niu, Aolei, Wang, Suwan, Zou, Chenhang, Harris, Raymond C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548101/
https://ncbi.nlm.nih.gov/pubmed/27745702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.08.020
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