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Shikonin suppresses proliferation and induces apoptosis in human leukemia NB4 cells through modulation of MAPKs and c-Myc

Acute promyelocytic leukemia (APL) is a special subtype of acute myeloid leukemia that responds to treatment with all-trans retinoic acid and arsenic trioxide. However, severe side effects and drug resistance limit the effectiveness of these treatments. Hence, new drugs for APL are required urgently...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Shan, Zhi-Ling, Zhong, Liang, Xiao, Chu-Lan, Gan, Liu-Gen, Xu, Ting, Song, Hao, Yang, Rong, Li, Liu, Liu, Bei-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548061/
https://ncbi.nlm.nih.gov/pubmed/28713949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6965
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