Hypertrophic differentiation of mesenchymal stem cells is suppressed by xanthotoxin via the p38-MAPK/HDAC4 pathway

Chondrocyte hypertrophy is a physiological process in endochondral ossification. However, the hypertrophic-like alterations of chondrocytes at the articular surface may result in osteoarthritis (OA). In addition, the generation of fibrocartilage with a decreased biological function in tissue enginee...

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Bibliografske podrobnosti
izdano v:Mol Med Rep
Main Authors: Cao, Zhen, Bai, Yun, Liu, Chuan, Dou, Ce, Li, Jianmei, Xiang, Junyu, Zhao, Chunrong, Xie, Zhao, Xiang, Qiang, Dong, Shiwu
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548016/
https://ncbi.nlm.nih.gov/pubmed/28677757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6886
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